After its second 38-point win in three weeks, the Detroit Lions (6-1) look to stay hot Sunday when they head to Lambeau Field to face the Green Bay Packers (6-2) at 4:25 p.m. ET on FOX.
The Lions are favored by 3.5 points across Michigan betting sites after last week's 52-14 beatdown over the Tennessee Titans to extend a five-game winning streak.
The Packers are riding their own four-game run after beating the Jacksonville Jaguars last week, but that win came at a cost with Jordan Love (groin) suffering an injury that could sideline him Sunday.
That would be a major blow for Green Bay, which would seize first place in the NFC North with a Week 9 win against its division rival.
Here is our Lions vs. Packers betting preview, betting odds and predictions for Sunday's matchup.
It's impossible to break down this game without focusing first and foremost on Love's status for Sunday.
The Packers quarterback suffered a groin injury in the first quarter of last week's win and played through it before leaving early in the third quarter.
He told reporters Wednesday that there's a "realistic" chance he plays this Sunday, even as he misses practice ahead of this pivotal NFC North showdown.
Love isn't the only player carrying an injury designation into Sunday's matchup, either.
Jared Goff (ankle) missed practice this week and said he's a "little sore" but plans to play Sunday in the midst of an MVP-level campaign for the Lions.
It's a similar story for Packers top rusher Josh Jacobs (ankle), who has also vowed to suit up this weekend after sitting out late in last week's win.
His health becomes an even bigger factor if Love can't go, as Green Bay's offense became especially reliant on the Pro Bowl back when Malik Willis was under center.
The Lions initially opened as -4.5 favorites on the point spread last Sunday and even touched -5 at some shops, but point spread betting immediately pushed the line in the Packers' favor.
Now, in the days ahead of kickoff, Detroit is laying 3.5 points across most of the best Michigan sportsbooks with reduced odds on the favorites.
You can bet the Lions -3 at BetRivers Sportsbook at -118 odds, which is the best price available for the road favorites as of this writing.
You'll need to pay extra to grab the Packers +3.5, which is dealing no better than -115 odds at DraftKings Sportsbook.
If you don't want to lay the points, you can bet on the Lions to win outright at -170 odds via Caesars Sportsbook.
Those moneyline betting odds would turn a winning $10 bet into a $5.88 profit if Detroit can beat its division rival and extend its lead in the NFC North.
While there's plenty of uncertainty surrounding the Packers offense, I have a lot more confidence in what we'll see when the Lions have the ball.
It's been a similar story every week for offensive coordinator Ben Johnson, who has engineered the NFL's best scoring offense (33.4 PPG) after last week's 52-point outburst against Tennessee.
That marked the fourth straight game this unit has scored at least 31 points behind an MVP-caliber quarterback and an unstoppable two-headed rushing attack.
Green Bay's defense has looked better under new defensive coordinator Jeff Hafley, but that unit is coming off its worst showing of the season last week against the Jaguars.
Trevor Lawrence and Co. scored on five of their final eight drives last week and finished with 390 total yards, which included multiple deep shots downfield against a vulnerable secondary.
That could be a continued issue this week with starting cornerback Jaire Alexander (knee) and safety Evan Williams (hamstring) both missing practice. If they don't play, expect Goff - who leads the NFL in yards per attempt (9.0) - to take advantage.
The Packers also missed 15 tackles in that loss to Jacksonville, per PFF. That's a bad sign ahead of Sunday's matchup against David Montgomery (10) and Jahmyr Gibbs (seven), who both rank in the top 15 in broken tackles.
Goff has completed 83 percent of his passes over his last five starts, which is the best such mark in NFL history.
He only finished with 12 completions last week, but he still finished with multiple passing touchdowns (three) for the fifth consecutive game.
I love his chances of exploiting Green Bay's secondary on Sunday. He's priced at -110 to throw two or more TDs at BetMGM Sportsbook, which would turn a winning $10 bet into a $9.09 profit.
I'm also skeptical that Jacobs can break through against this elite Lions rush defense - especially if Aaron Glenn's defense can key in the run with Willis or an injured Love under center.
His player props aren't available as of this writing with Love's status unclear. He ran for 127 yards last week, but don't be surprised if he falls short of 80 yards for the sixth time in seven weeks.
Given Love's uncertain status for Sunday, I'd be awfully tempted to lay the points on Detroit in what would be an imminently winnable game against an incomplete Packers offense and reeling defense.
If Love suits up, though, I can see the appeal on the home 'dogs catching more than a field goal in a critical NFC South showdown. For as good as the Lions' defense has been at times, it's vulnerable on the back end and could be exposed against a deep-ball merchant like Love - and those plays could swing the whole game.
That's why I'm staying away from the point spread and instead betting on the Lions to score Over 27.5 points at +130 odds. If they do that for a fifth straight game, a $10 bet at FanDuel Sportsbook would return a $13 profit.