Cohesin Drives Chromatin Scanning During RAD51 Homology Search - News Directory 3

Our genomes aren't simply long, linear strands of DNA. They're intricately folded into complex three-dimensional structures, a process vital for regulating gene expression and maintaining genomic stability. A key player in this folding is a protein complex called cohesin,wich creates loops within the chromatin - the material that makes up our chromosomes. For years, scientists have debated the precise roles of these loops, but recent research reveals a surprising trigger for their formation: DNA damage.